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The key methodology that makes all the disciplines work together to yield the best overall formulation is called Desirability. Desirability is the latest advance in optimization technology.

SmartD Technology

desirability curve SynGenics has applied the concept of desirability for many years to factor market requirements and engineering information in the optimization of compounds and analysis of technologies. Now SmartD Technology insures that the desirability function has a derivative over the entire range of each property variable eliminating unnatural distortion of the solution hypersurface.

Ease of Use

For the novice, no setup is required. For the expert user, there is great flexibility of function shape implemented by passing the curve through user defined set points in property units. There are no hard-to-understand shape factors. Shown here is a Target desirability function for a property variable Mod10%. The shape points are automatically placed in the center of the range as on the right side of the curve, and can be moved when the practiced user has reason to reshape the curve, as shown on the left side.

Surface Plot

surface plot Once ImproveIt finds a solution, you can use its 3-dimensional graphics to gain insight into the relationships it searched to find the best formulation. Sometimes this can be the most valuable part of the exercise, because you finally can see what the PC has been wrestling with in the realm of numbers! ImproveIt incorporates the wisdom of the formulator in an easy-to-use, step-by-step approach. Several items have default values so the new user can achieve success before deep knowledge is acquired. Of course, the more experience you already have, the more benefit you will derive from using this application. Windows-based, ImproveIt is compatible with 95, 98, NT, 2000, and XP. All the standard features, such as cut and paste, importing and exporting data, and linking to other documents are available in ImproveIt.
Summary Information
ImproveIt is the advanced tool for statistical analysis and compounding and formulation optimization. ImproveIt brings together the following disciplines: multiple regression
  1. Statistical Design of Experiments Statistical Design of Experiments is a powerful body of statistically based techniques that allow a scientist or engineer to efficiently characterize a design space and to establish the link between cause and effect for processes that have multiple input factors and associated interactions.
  2. Response Surface Methodology In statistics, response surface methodology (RSM) explores the relationships between several explanatory variables and one or more response variables.
  3. Multiple Regression is a statistical technique that predicts values of one variable on the basis of two or more other variables;
  4. Variance Partition Analysis;
  5. Optimization to address the formulation problem